翻訳と辞書
Words near each other
・ Tetanostola
・ Tetanurae
・ Tetanus
・ Tetanus vaccine
・ Tetany
・ Tetapaga Lake
・ Tetapaga Syncline
・ Tetara
・ Testing Mom
・ Testing Positive 4 the Funk
・ Testing reliability
・ Testing the Waters
・ Testing the waters
・ Testing Times
・ Testing, adjusting, balancing
Testis determining factor
・ TestLink
・ Testman, U.S. Virgin Islands
・ TestNG
・ Testo (rapper)
・ Testo Junkie
・ Testolactone
・ Teston
・ Teston (disambiguation)
・ Teston Bridge
・ Teston Crossing Halt railway station
・ Teston, Ontario
・ Testoni
・ Testonites
・ Testoni–Valla rivalry


Dictionary Lists
翻訳と辞書 辞書検索 [ 開発暫定版 ]
スポンサード リンク

Testis determining factor : ウィキペディア英語版
Testis determining factor

Testis-determining factor (TDF), also known as sex-determining region Y (SRY) protein, is a DNA-binding protein (also known as gene-regulatory protein/transcription factor) encoded by the ''SRY'' gene that is responsible for the initiation of male sex determination in humans. SRY is an intronless sex-determining gene on the Y chromosome in therians (placental mammals and marsupials); mutations in this gene lead to a range of sex-related disorders with varying effects on an individual's phenotype and genotype.
TDF is a member of the SOX (SRY-like box) gene family of DNA-binding proteins. When complexed with the SF1 protein, TDF acts as a transcription factor that can upregulate other transcription factors, most importantly SOX9.〔 Its expression causes the development of primary sex cords, which later develop into seminiferous tubules. These cords form in the central part of the yet-undifferentiated gonad, turning it into a testis. The now-induced Leydig cells of the testis then start secreting testosterone, while the Sertoli cells produce anti-Müllerian hormone. SRY gene effects normally take place 6–8 weeks after foetus formation and inhibits the female anatomical structural growth in males. It also works towards developing the dominant male characteristics.
== Gene evolution and regulation ==


抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)
ウィキペディアで「Testis determining factor」の詳細全文を読む



スポンサード リンク
翻訳と辞書 : 翻訳のためのインターネットリソース

Copyright(C) kotoba.ne.jp 1997-2016. All Rights Reserved.